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Theory of Mind in the Early Course of Schizophrenia

[ Vol. 13 , Issue. 2 ]

Author(s):

Nora S. Vyas, Yi Wang, Shemin S. Vyas, Eoin Killackey, Tor-Arne Haugland and Raymond C.K. Chan   Pages 102 - 110 ( 9 )

Abstract:


Theory of mind deficit is a core feature of schizophrenia and is considered a vulnerability marker of the disorder. The majority of studies measuring theory of mind in schizophrenia involve multiple-episode or chronic schizophrenia patients, and therefore it is important to delineate whether these deficits occur before or following illness-onset by assessing high-risk subjects (clinical high risk and ultra-high risk), early-onset psychosis, and first-degree relatives. We address the question of whether theory of mind impairment is specific or a facet of general cognitive impairment in these clinical populations, and incorporate genetic and neuroimaging studies on the theory of mind. The review provides a succinct evaluation of the literature, discusses current limitations and proposes future directions.

Keywords:

Theory of mind, adolescence, neuroimaging, social cognition, unaffected relatives, high risk, endophenotype, mentalising.

Affiliation:

Department of Psychology, Kingston University London, Penrhyn Road, Kingston upon Thames, Surrey, KT1 2EE, Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, University College Hospital, University College London Hospitals NHS Foundation Trust, 235 Euston Road, Bloomsbury, London, NW1 2BU; Boston Pilgrim Hospital, United Lincolnshire Healthcare NHS Trust, Sibsey Road, Boston, Lincolnshire, PE21 9QS, Orygen Youth Health Research Centre, 35 Poplar Road, Parkville, Victoria 3052, Department of Psychology, Kingston University London, Penrhyn Road, Kingston upon Thames, Surrey, KT1 2EE, Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing



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